Which of the following monoclonal antibodies is a TNF-alpha inhibitor used extensively in the treatment of Rheumatoid Arthritis and Crohn's disease?
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Correct answer: Infliximab
Infliximab is a chimeric monoclonal antibody that binds with high affinity to soluble and transmembrane forms of TNF-alpha. By neutralizing this cytokine, it inhibits the inflammatory cascade responsible for joint and bowel tissue damage.
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