What does the 'xi' in the name of the monoclonal antibody Rituximab indicate about its structure?
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Correct answer: It is a chimeric antibody with human and mouse regions
The infix '-xi-' denotes a chimeric antibody, typically consisting of approximately 65% human and 35% mouse protein. This design helps reduce the immunogenicity compared to pure murine antibodies while maintaining high binding affinity.
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