Sedatives and Hypnotics · Pharmacology

Benzodiazepines are generally avoided in patients with sleep apnea because they:

  1. Increase the respiratory drive's sensitivity to carbon dioxide
  2. Relax upper airway muscles and blunt arousal from hypoxia
  3. Cause significant weight gain that narrows the airway
  4. Induce vivid nightmares that fragment REM sleep
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Correct answer: Relax upper airway muscles and blunt arousal from hypoxia

In patients with obstructive sleep apnea (OSA), benzodiazepines can worsen the condition by further relaxing the pharyngeal muscles and suppressing the brain's ability to wake the patient up when oxygen levels drop.

Difficulty: Medium Question 19 of 20

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