Mood Stabilizers · Pharmacology

Valproic acid (Divalproex) is often preferred over Lithium for which specific clinical presentation of Bipolar Disorder?

  1. Rapid-cycling Bipolar Disorder
  2. Classic euphoric mania
  3. Bipolar depression in pregnancy
  4. Uncomplicated Type II Bipolar Disorder
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Correct answer: Rapid-cycling Bipolar Disorder

Valproic acid has shown superior efficacy in treating 'rapid-cycling' (four or more episodes per year) and mixed episodes compared to lithium. It works by increasing GABA levels and blocking voltage-gated sodium channels.

Difficulty: Medium Question 4 of 20

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