Etomidate is often used for the induction of anesthesia in patients with cardiovascular instability, but it is known to inhibit which process?
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Correct answer: Adrenal cortisol synthesis
Etomidate inhibits the enzyme 11-beta-hydroxylase, which is essential for the synthesis of cortisol and aldosterone. Even a single induction dose can cause transient adrenal suppression, which may be problematic in septic or critically ill patients.
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