Blockade of dopamine receptors in the tuberoinfundibular pathway by antipsychotics leads to which of the following adverse effects?
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Correct answer: Hyperprolactinemia
Dopamine normally inhibits prolactin release from the anterior pituitary. When D2 receptors in the tuberoinfundibular pathway are blocked, prolactin levels rise, potentially causing galactorrhea, gynecomastia, and sexual dysfunction.
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