Antiplatelet Drugs · Pharmacology

How long before an elective surgery should Aspirin typically be discontinued to allow for the restoration of normal platelet function?

  1. 12 hours
  2. 24 to 48 hours
  3. 7 to 10 days
  4. 3 weeks
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Correct answer: 7 to 10 days

Because Aspirin irreversibly inhibits platelets and the average lifespan of a platelet is about 7 to 10 days, the drug must be stopped at least a week prior to surgery to ensure that a sufficient population of new, functional platelets is present.

Difficulty: Medium Question 11 of 20

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