Cholinergic Antagonists · Pharmacology

What happens to the gastric emptying rate after the administration of a muscarinic antagonist?

  1. It increases significantly
  2. It is markedly delayed
  3. It remains unchanged
  4. It briefly slows and then accelerates
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Correct answer: It is markedly delayed

Parasympathetic activity promotes GI motility. Blocking muscarinic receptors reduces the tone and peristalsis of the stomach and intestines, resulting in delayed gastric emptying and constipation.

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