Which cholinergic antagonist is used via inhalation to produce bronchodilation in patients with COPD while minimizing systemic side effects?
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Correct answer: Ipratropium
Ipratropium is a quaternary ammonium derivative of atropine. Because it is highly polar and poorly absorbed into the systemic circulation, it provides localized bronchodilation when inhaled with minimal side effects like dry mouth or tachycardia.
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