Adrenergic Antagonists · Pharmacology

Timolol is commonly used topically in the eye to treat glaucoma. What is its mechanism of action in this setting?

  1. Increasing the drainage of aqueous humor through the canal of Schlemm
  2. Reducing the production of aqueous humor by the ciliary body
  3. Causing miosis to open the iridocorneal angle
  4. Paralyzing the ciliary muscle
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Correct answer: Reducing the production of aqueous humor by the ciliary body

Beta-blockers like Timolol reduce intraocular pressure by decreasing the secretion of aqueous humor from the ciliary processes. This makes them a mainstay in the treatment of open-angle glaucoma.

Difficulty: Medium Question 14 of 20

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