Antifungal Drugs · Pharmacology

Which fungal cell membrane component is the main target of many antifungal drugs?

  1. Chitin
  2. Beta-glucan
  3. Ergosterol
  4. Cholesterol
Show answer and explanation

Correct answer: Ergosterol

Ergosterol is the principal sterol of the fungal cell membrane, the role cholesterol plays in human membranes. Polyenes bind it directly and azoles and allylamines block its synthesis, while chitin and beta-glucan belong to the cell wall, not the membrane.

Difficulty: Easy Question 12 of 20

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