Respiratory Pathology · Pathology

Which of the following describes the characteristic lesion of 'Ghon complex' in primary tuberculosis?

  1. A necrotic area in the apex of the lung only
  2. A peripheral parenchymal granuloma and an involved regional lymph node
  3. Diffuse miliary seeding throughout both lungs
  4. A large cavity filled with Aspergillus hyphae
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Correct answer: A peripheral parenchymal granuloma and an involved regional lymph node

A Ghon complex consists of a small subpleural granuloma (Ghon focus) combined with granulomatous inflammation in the draining hilar lymph nodes. This is the classic presentation of primary TB infection.

Difficulty: Medium Question 8 of 20

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