A biopsy of a lung mass reveals small, round-to-oval cells with scant cytoplasm, 'salt and pepper' chromatin, and frequent nuclear molding. What is the most likely diagnosis?
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Correct answer: Small cell carcinoma
Small cell carcinoma is a high-grade neuroendocrine tumor characterized by small cells with minimal cytoplasm and finely granular (salt and pepper) chromatin. Nuclear molding is a distinctive feature caused by the close apposition of cells with scant cytoplasm.
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