Which of the following features is a common nuclear change seen in malignant cells but rarely in benign ones?
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Correct answer: High nuclear-to-cytoplasmic (N/C) ratio
Malignant cells often exhibit enlarged nuclei, resulting in a high N/C ratio approaching 1:1 rather than the normal 1:4 or 1:6. This reflects increased DNA content and high metabolic activity associated with cancer.
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More Benign and Malignant Tumors questions
- The term 'Carcinoma' specifically refers to a malignant tumor arising from which tissue type?
- Which of the following is an example of a 'benign-sounding' name that actually refers to a highly malignant tumor?
- What is a 'Hamartoma'?
- Which pathway of metastasis is most commonly used by carcinomas?
- Which of the following is a characteristic of 'Pleomorphism' in tumor cells?
- What is 'Carcinoma in situ' (CIS)?