Benign and Malignant Tumors · Pathology

What is 'Carcinoma in situ' (CIS)?

  1. A benign tumor that has the potential to become malignant
  2. Malignant cells confined within the basement membrane
  3. A tumor that has spread to distant organs
  4. A mesenchymal tumor that is localized
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Correct answer: Malignant cells confined within the basement membrane

CIS represents a pre-invasive stage of malignancy where cells show all the cytological features of cancer but remain confined by the basement membrane. Once the basement membrane is penetrated, it is classified as invasive carcinoma.

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