What is the primary mechanism of tissue damage in infections caused by Clostridium perfringens (Gas Gangrene)?
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Correct answer: Production of Alpha-toxin (lecithinase) that degrades cell membranes
Clostridium perfringens produces alpha-toxin, a phospholipase (lecithinase) that destroys red blood cells and platelets while causing extensive myonecrosis. This leads to the characteristic gas production and rapid tissue destruction seen in gas gangrene.
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