Bacterial Infections · Pathology

Which of the following describes the characteristic intestinal lesion seen in Typhoid Fever (Salmonella typhi)?

  1. Flask-shaped ulcers in the colon
  2. Longitudinal ulcers over Peyer's patches in the terminal ileum
  3. Transmural inflammation with skip lesions
  4. Pseudomembranes composed of fibrin and neutrophils
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Correct answer: Longitudinal ulcers over Peyer's patches in the terminal ileum

Salmonella typhi targets the lymphoid tissue of the small intestine. It causes hyperplasia and subsequent necrosis of Peyer's patches, resulting in oval or longitudinal ulcers that carry a risk of perforation.

Difficulty: Medium Question 6 of 20

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