Megaloblastic Anemia · Pathology

What is the 'Schilling test' historically used to evaluate?

  1. The rate of DNA synthesis in the marrow
  2. The cause of Vitamin B12 malabsorption
  3. The level of serum folate
  4. The presence of G6PD deficiency
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Correct answer: The cause of Vitamin B12 malabsorption

The Schilling test used radioactive B12 to determine if a patient's B12 deficiency was due to dietary lack, intrinsic factor deficiency (Pernicious Anemia), or ileal malabsorption. It has largely been replaced by antibody testing.

Difficulty: Medium Question 17 of 20

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