Which of the following mechanisms classifies G6PD deficiency as an anemia?
Show answer and explanation
Correct answer: Increased susceptibility to oxidative stress and hemolysis
G6PD deficiency is an enzyme defect that prevents the regeneration of NADPH. Without NADPH, RBCs cannot maintain reduced glutathione, making them vulnerable to oxidative damage and subsequent hemolysis.
Keep practicing
More Anemia Classification questions
- Basophilic stippling of red blood cells is most classically associated with which type of microcytic anemia?
- A 'Dimorphic' red cell population (both microcytic and normocytic cells) is often seen in:
- Which classification of anemia is most likely in a patient with chronic alcoholism and liver disease without vitamin deficiency?
- The presence of 'Bite cells' and 'Heinz bodies' is characteristic of which hemolytic process?
- Which of the following classifies an anemia as 'Aplastic'?
- A patient with a gastrectomy history has an MCV of 115 fL. What is the most likely pathological mechanism?