Cell Death: Necrosis · Pathology

Which enzyme is primarily responsible for the liquefaction in liquefactive necrosis during an abscess formation?

  1. Pancreatic lipase
  2. Caspase-3
  3. Leukocytic lysosomal enzymes
  4. Cytochrome c
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Correct answer: Leukocytic lysosomal enzymes

In an abscess or focal bacterial infection, neutrophils and other leukocytes release powerful lysosomal enzymes. These enzymes digest (liquefy) the dead cells and surrounding tissue, creating the characteristic pus.

Difficulty: Medium Question 10 of 20

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