Cell Death: Necrosis · Pathology

Microscopic examination of a kidney biopsy shows preserved cell outlines but a total loss of nuclei. This is characteristic of:

  1. Liquefactive necrosis
  2. Coagulative necrosis
  3. Caseous necrosis
  4. Apoptosis
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Correct answer: Coagulative necrosis

Coagulative necrosis is characterized by 'ghost cells'—cells that retain their basic structural outline and tissue architecture, but have lost their nuclei and cytoplasmic detail due to protein denaturation.

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