Gastritis · Pathology

Which laboratory finding is most consistent with autoimmune gastritis?

  1. Hypogastrinemia
  2. Hyperchlorhydria
  3. Hypergastrinemia
  4. Decreased serum chromogranin A
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Correct answer: Hypergastrinemia

The loss of acid-producing parietal cells in autoimmune gastritis leads to achlorhydria. The lack of negative feedback by acid triggers G cells in the antrum to hypersecrete gastrin, resulting in hypergastrinemia.

Difficulty: Medium Question 7 of 20

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