Which of the following is a potential complication of the hypergastrinemia seen in autoimmune gastritis?
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Correct answer: Neuroendocrine (Carcinoid) tumor
Gastrin has a trophic effect on enterochromaffin-like (ECL) cells. Prolonged hypergastrinemia in autoimmune gastritis can lead to ECL cell hyperplasia and the eventual development of low-grade neuroendocrine tumors.
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