Thyroid Disorders · Pathology

A 40-year-old male presents with a painful, enlarged thyroid gland following a viral upper respiratory tract infection. Histology shows granulomatous inflammation with multinucleated giant cells. What is the diagnosis?

  1. Hashimoto thyroiditis
  2. Subacute Granulomatous (De Quervain) thyroiditis
  3. Subacute Lymphocytic thyroiditis
  4. Anaplastic carcinoma
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Correct answer: Subacute Granulomatous (De Quervain) thyroiditis

De Quervain thyroiditis is typically triggered by a viral infection and presents with neck pain and systemic symptoms. The histological hallmark is granulomatous inflammation with giant cells surrounding fragmented thyroid follicles.

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