Diabetes Mellitus · Pathology

Which of the following describes 'Insulitis'?

  1. Fibrosis of the exocrine pancreas
  2. Leukocytic infiltration of the islets in Type 1 DM
  3. Hypertrophy of the islets in neonates of diabetic mothers
  4. Necrosis of the islets due to acute pancreatitis
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Correct answer: Leukocytic infiltration of the islets in Type 1 DM

Insulitis is an inflammatory lesion of the islets characterized by lymphocytic infiltration (mainly T-cells). It is primarily seen in the early stages of Type 1 Diabetes as the immune system attacks the beta cells.

Difficulty: Medium Question 9 of 20

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