Diabetes Mellitus · Pathology

In the context of diabetic retinopathy, what defines the 'proliferative' stage?

  1. Microaneurysms and hard exudates
  2. Neovascularization from retinal ischemia
  3. Macular edema without vessel growth
  4. Thickening of the retinal basement membrane
Show answer and explanation

Correct answer: Neovascularization from retinal ischemia

Proliferative retinopathy is characterized by neovascularization, often driven by VEGF in response to retinal ischemia. These new vessels are fragile and can lead to vitreous hemorrhage or retinal detachment.

Difficulty: Medium Question 12 of 20

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