Inflammatory Skin Disorders · Pathology

Which histological feature is the hallmark of psoriasis?

  1. Subepidermal bullae with eosinophils
  2. Acanthosis, parakeratosis, and Munro microabscesses
  3. Interface dermatitis with a band-like lymphocytic infiltrate
  4. Suprabasal acantholysis with 'tombstone' appearance
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Correct answer: Acanthosis, parakeratosis, and Munro microabscesses

Psoriasis is characterized by regular acanthosis (rete ridge elongation), parakeratosis containing neutrophils (Munro microabscesses), and a diminished or absent stratum granulosum. These features reflect the rapid epidermal turnover seen in the disease.

Difficulty: Medium Question 1 of 20

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