What is the characteristic histological finding in Erythema Multiforme?
Show answer and explanation
Correct answer: Civatte bodies and vacuolar interface change
Erythema multiforme features vacuolar degeneration of the basal layer and scattered necrotic keratinocytes. In severe cases, this progresses to full-thickness epidermal necrosis, as seen in Stevens-Johnson syndrome.
Keep practicing
More Inflammatory Skin Disorders questions
- Which of the following describes 'Spongiosis' in the context of acute eczematous dermatitis?
- A skin biopsy shows 'test tube in a rack' rete ridge lengthening, thinning of the suprapapillary plates, and Kogoj pustules. What is the di…
- Which of the following is an example of an interface dermatitis with a 'saw-tooth' pattern of epidermal hyperplasia?
- Wickham striae are clinical white lines on the surface of papules associated with which condition?
- Which inflammatory skin disorder is associated with a 'Herald patch' followed by a 'Christmas tree' distribution of lesions?
- Direct immunofluorescence of a skin biopsy shows IgA deposits in a 'granular' pattern at the tips of dermal papillae. This is diagnostic fo…