Bullous Diseases · Pathology

Dermatitis herpetiformis is pathologically characterized by the presence of which of the following?

  1. Acantholysis within the granular layer
  2. Neutrophilic microabscesses at the papillary tips
  3. Linear IgA deposition along the entire basement membrane
  4. Full thickness epidermal necrosis
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Correct answer: Neutrophilic microabscesses at the papillary tips

Dermatitis herpetiformis features neutrophilic microabscesses at the tips of dermal papillae. This leads to small subepidermal vesicles and is strongly associated with gluten-sensitive enteropathy.

Difficulty: Medium Question 4 of 20

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