Which of the following describes the cytological features of High-grade Squamous Intraepithelial Lesion (HSIL)?
Show answer and explanation
Correct answer: Cells with a high nuclear-to-cytoplasmic ratio and coarse chromatin
HSIL is characterized by cells that are generally smaller than LSIL cells but possess much higher N/C ratios. The nuclei show significant irregularities, hyperchromasia, and coarse chromatin, reflecting more advanced precancerous changes.
Keep practicing
More Pap Smear questions
- What is the primary advantage of Liquid-Based Cytology (LBC) over the conventional Pap smear?
- The presence of 'clue cells' in a Pap smear is characteristic of which condition?
- How do Trichomonas vaginalis organisms typically appear in a Papanicolaou-stained smear?
- A Pap smear showing 'LSIL' (Low-grade Squamous Intraepithelial Lesion) corresponds to which histological grade?
- What is the significance of finding 'Endocervical Cells' in a Pap smear from a premenopausal woman?
- Which cytological finding is most suggestive of an infection with Herpes Simplex Virus (HSV)?