Urinalysis · Pathology

A patient's urine sample turns dark brown or black after standing at room temperature. Which condition should be suspected?

  1. Alkaptonuria
  2. Biliary obstruction
  3. Myoglobinuria
  4. Porphyria
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Correct answer: Alkaptonuria

Alkaptonuria is an inherited disorder where homogentisic acid is excreted in the urine. Upon exposure to air and light (alkalinity), the homogentisic acid oxidizes and polymerizes, turning the urine dark.

Difficulty: Medium Question 5 of 20

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