Hypertension Pathology · Pathology

Which renal condition is a common cause of secondary hypertension due to activation of the Renin-Angiotensin-Aldosterone System (RAAS)?

  1. Renal artery stenosis
  2. Acute tubular necrosis
  3. Nephrolithiasis
  4. Minimal change disease
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Correct answer: Renal artery stenosis

Renal artery stenosis decreases perfusion to the kidney, which the juxtaglomerular apparatus perceives as low blood pressure. This triggers the release of renin, leading to systemic vasoconstriction and sodium retention (Goldblatt kidney mechanism).

Difficulty: Medium Question 7 of 20

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