Hypertension Pathology · Pathology

Which of the following describes the 'Goldblatt kidney' phenomenon?

  1. Hypertrophy of a kidney due to excess growth hormone
  2. Atrophy of a kidney due to renal artery stenosis with contralateral hypertension
  3. Bilateral kidney enlargement in polycystic kidney disease
  4. Formation of multiple renal stones in hyperparathyroidism
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Correct answer: Atrophy of a kidney due to renal artery stenosis with contralateral hypertension

The Goldblatt kidney model demonstrates that unilateral renal artery stenosis leads to renin-mediated hypertension. The stenotic kidney becomes atrophic, while the contralateral kidney may show changes of hypertensive damage due to the high systemic pressure.

Difficulty: Medium Question 10 of 20

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