Hypertension Pathology · Pathology

Which of the following is the characteristic morphological change seen in the small arteries of patients with benign hypertension?

  1. Hyperplastic arteriolosclerosis
  2. Diffuse hyaline arteriolosclerosis
  3. Arteriolar fibrinoid necrosis
  4. Monckeberg medial calcific sclerosis
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Correct answer: Diffuse hyaline arteriolosclerosis

Hyaline arteriolosclerosis is the hallmark of benign hypertension and diabetes. It is characterized by pink, homogeneous hyaline thickening of the arteriolar walls with associated luminal narrowing due to leaked plasma proteins and increased matrix synthesis.

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