What is the primary mechanism behind the development of 'Fibrinoid Necrosis' in malignant hypertension?
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Correct answer: Acute vascular injury with plasma protein leakage
Fibrinoid necrosis occurs in malignant hypertension when extreme blood pressure causes acute damage to the endothelium. This allows fibrin and other plasma proteins to leak into the vessel wall, resulting in a bright pink, necrotic appearance on H&E stain.
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