Acute vs Chronic Kidney Disease · NCLEX Exam

Which laboratory pattern is most characteristic of AKI rather than CKD?

  1. Gradual monthly rise in creatinine
  2. Sudden doubling of serum creatinine in 48 hours
  3. Stable elevated creatinine for many months
  4. eGFR persistently < 30 mL/min/1.73m² for at least 3 months
Show answer and explanation

Correct answer: Sudden doubling of serum creatinine in 48 hours

AKI is defined by an abrupt increase in creatinine or decrease in urine output within hours to days. The other patterns better align with chronic disease.

Difficulty: Medium Question 6 of 18

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