Urinary System

Acute and Chronic Renal Failure Practice Questions

20 free Acute and Chronic Renal Failure practice questions for the NCLEX Exam. Tap an option to answer — you get instant feedback, the correct answer, and a detailed explanation for every question.

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Question 1 of 20 Medium

What intervention should the nurse expect to perform first for a client with acute renal failure and serum potassium of 6.8 mEq/L?

  1. A Administer sodium polystyrene sulfonate
  2. B Restrict dietary potassium
  3. C Administer IV calcium gluconate
  4. D Prepare for dialysis tomorrow

Correct answer: Administer IV calcium gluconate

IV calcium gluconate stabilizes the cardiac membrane to prevent life-threatening arrhythmias from hyperkalemia, making it the priority before other interventions.

Question 2 of 20 Medium

In chronic kidney disease (CKD), which laboratory value improves when a patient is prescribed erythropoietin?

  1. A Serum creatinine
  2. B Hemoglobin
  3. C Calcium
  4. D Potassium

Correct answer: Hemoglobin

Erythropoietin stimulates red blood cell production, improving hemoglobin and hematocrit levels in CKD-related anemia.

Question 3 of 20 Medium

What clinical finding is most characteristic of acute tubular necrosis (ATN)?

  1. A Polyuria with dilute urine
  2. B Oliguria with muddy brown casts
  3. C High specific gravity with proteinuria
  4. D Hematuria without casts

Correct answer: Oliguria with muddy brown casts

ATN presents with oliguria and urine containing muddy brown granular casts due to tubular cell injury.

Question 4 of 20 Medium

Which condition is a common cause of prerenal acute kidney injury (AKI)?

  1. A Kidney stones
  2. B Hypovolemia
  3. C Acute glomerulonephritis
  4. D Bladder outlet obstruction

Correct answer: Hypovolemia

Prerenal AKI results from decreased renal perfusion, most commonly due to hypovolemia or hypotension.

Question 5 of 20 Medium

What dietary instruction should be given to a client with chronic renal failure?

  1. A Increase protein intake
  2. B Restrict phosphorus and potassium
  3. C Increase dairy products for calcium
  4. D Increase sodium for hydration

Correct answer: Restrict phosphorus and potassium

Phosphorus and potassium accumulate in CKD; their restriction helps prevent hyperphosphatemia and hyperkalemia.

Question 6 of 20 Medium

During the oliguric phase of acute renal failure, what complication should the nurse closely monitor for?

  1. A Hypokalemia
  2. B Hyponatremia
  3. C Metabolic alkalosis
  4. D Hypovolemia

Correct answer: Hyponatremia

Sodium becomes diluted due to fluid retention, leading to hyponatremia and potential neurological symptoms.

Question 7 of 20 Medium

A client with end-stage renal disease (ESRD) reports muscle cramps during hemodialysis. What is the likely cause?

  1. A Hypocalcemia
  2. B Hypotension and fluid shifts
  3. C Hypernatremia
  4. D Elevated urea

Correct answer: Hypotension and fluid shifts

Rapid fluid and electrolyte shifts during dialysis can lead to hypotension and muscle cramps.

Question 8 of 20 Medium

Which lab result indicates the most significant improvement in kidney function in a patient with AKI?

  1. A Increased urine output
  2. B Decreased serum creatinine
  3. C Decreased urine specific gravity
  4. D Elevated BUN

Correct answer: Decreased serum creatinine

Serum creatinine is a reliable indicator of renal function; its decline suggests recovery.

Question 9 of 20 Medium

What order should the nurse question for a patient in end-stage renal disease?

  1. A Erythropoietin injection
  2. B High-protein diet
  3. C Phosphate binders
  4. D Fluid restriction

Correct answer: High-protein diet

Protein breakdown produces nitrogenous wastes that kidneys cannot excrete; thus, high-protein diets are avoided.

Question 10 of 20 Medium

A client in acute renal failure is placed on a fluid restriction of 600 mL/day. What is the best nursing rationale for this order?

  1. A To reduce cardiac workload
  2. B To prevent pulmonary edema
  3. C To decrease urine output
  4. D To stimulate diuresis

Correct answer: To prevent pulmonary edema

Fluid overload in renal failure can cause pulmonary edema; restricting fluids helps prevent respiratory compromise.

Question 11 of 20 Medium

Which statement by a patient with chronic kidney disease indicates a need for further teaching?

  1. A “I should take my phosphate binder with meals.”
  2. B “I should weigh myself daily.”
  3. C “I can use salt substitutes instead of table salt.”
  4. D “I should limit dairy products.”

Correct answer: “I can use salt substitutes instead of table salt.”

Salt substitutes often contain potassium, which can lead to hyperkalemia in CKD.

Question 12 of 20 Medium

A patient with chronic renal failure has an elevated parathyroid hormone (PTH) level primarily due to which factor?

  1. A Hyperkalemia from impaired potassium excretion
  2. B Hypocalcemia from phosphate retention
  3. C Increased intestinal calcium absorption
  4. D Dehydration from excessive fluid loss

Correct answer: Hypocalcemia from phosphate retention

Phosphate retention binds calcium, causing hypocalcemia and secondary hyperparathyroidism.

Question 13 of 20 Medium

What should the nurse's first action be upon noting a patient’s urine output of 100 mL in 8 hours?

  1. A Increase IV fluids
  2. B Notify the physician
  3. C Check for bladder distention
  4. D Document and continue monitoring

Correct answer: Check for bladder distention

Oliguria may result from urinary retention; assessment for bladder distention is a critical first step.

Question 14 of 20 Medium

What is the main goal in managing acute glomerulonephritis?

  1. A Encourage high fluid intake
  2. B Reduce renal inflammation
  3. C Administer nephrotoxic antibiotics
  4. D Increase dietary potassium

Correct answer: Reduce renal inflammation

Glomerulonephritis involves immune-mediated inflammation; treatment focuses on reducing inflammation and preventing complications.

Question 15 of 20 Medium

Which symptom suggests uremic encephalopathy in chronic renal failure?

  1. A Jaundice and pruritus
  2. B Tremors and confusion
  3. C Chest pain and palpitations
  4. D Muscle weakness and cramping

Correct answer: Tremors and confusion

Accumulation of uremic toxins can affect the central nervous system, causing confusion, tremors, and decreased alertness.

Question 16 of 20 Medium

In advanced renal failure, which acid-base imbalance is anticipated?

  1. A Respiratory acidosis
  2. B Metabolic acidosis
  3. C Metabolic alkalosis
  4. D Respiratory alkalosis

Correct answer: Metabolic acidosis

Impaired renal excretion of hydrogen ions and bicarbonate loss cause metabolic acidosis.

Question 17 of 20 Medium

What electrocardiogram (ECG) finding is expected in chronic renal failure due to electrolyte imbalance?

  1. A U waves
  2. B Peaked T waves
  3. C Prolonged QT interval
  4. D Flattened P waves

Correct answer: Peaked T waves

Hyperkalemia causes peaked T waves due to delayed ventricular repolarization.

Question 18 of 20 Medium

Which intervention best helps prevent infection in a patient with a peritoneal dialysis catheter?

  1. A Flushing the catheter daily with heparin
  2. B Applying antibiotic ointment to the exit site
  3. C Maintaining sterile technique during exchanges
  4. D Irrigating the catheter with saline routinely

Correct answer: Maintaining sterile technique during exchanges

Strict sterile technique during exchanges is crucial to prevent peritonitis.

Question 19 of 20 Medium

How does the nurse evaluate the effectiveness of furosemide for a client with acute renal failure?

  1. A Weight gain
  2. B Increased urine output
  3. C Elevated potassium level
  4. D Decreased blood pressure

Correct answer: Increased urine output

Furosemide is a loop diuretic; increased urine output indicates effective diuresis.

Question 20 of 20 Medium

In a patient with end-stage renal disease (ESRD) prescribed aluminum hydroxide, what is the purpose of this drug?

  1. A Decrease potassium levels
  2. B Bind phosphate in the intestine
  3. C Stimulate red blood cell production
  4. D Increase calcium absorption

Correct answer: Bind phosphate in the intestine

Aluminum hydroxide binds dietary phosphate, reducing absorption and helping control hyperphosphatemia.

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