Hormone Replacement Therapy · NCLEX Exam

What is the most accurate statement regarding the timing of starting menopausal hormone therapy (MHT)?

  1. It is only considered safe when initiated after a woman reaches age 65
  2. The benefit-to-risk ratio is most favourable within 10 years of menopause
  3. It reliably prevents cardiovascular disease in essentially all treated women
  4. It is absolutely contraindicated whenever vasomotor symptoms are present
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Correct answer: The benefit-to-risk ratio is most favourable within 10 years of menopause

Guidelines indicate that initiating hormone therapy in women under ~60 years or within 10 years of menopause tends to yield more favourable benefits versus risks.

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