Tumor Lysis Syndrome and Oncologic Emergencies · NCLEX Exam

When is the use of Rasburicase particularly indicated in managing TLS?

  1. Uric acid levels remain normal before treatment
  2. Known pre-existing G6PD deficiency is present
  3. High-risk lymphoma with elevated uric acid and renal impairment
  4. Moderate-risk patient with fully intact renal function
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Correct answer: High-risk lymphoma with elevated uric acid and renal impairment

Rasburicase is indicated in high-risk TLS patients with elevated uric acid and renal impairment due to its rapid action on uric acid breakdown.

Difficulty: Medium Question 9 of 20

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