Tumor Lysis Syndrome and Oncologic Emergencies · NCLEX Exam

What nursing measure best helps reduce the risk of TLS in a patient with acute lymphoblastic leukemia and high WBC count starting induction chemo?

  1. Delay all hydration until after chemotherapy
  2. Start allopurinol prophylactically before therapy
  3. Administer potassium-rich maintenance fluids
  4. Monitor a complete blood count only once daily
Show answer and explanation

Correct answer: Start allopurinol prophylactically before therapy

Allopurinol given prophylactically helps prevent hyperuricemia and TLS before cytotoxic therapy.

Difficulty: Medium Question 12 of 20

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