Pathophysiology of Burn Injury · NCLEX Exam

What is the primary driver for the formation of massive edema in both burned and non‐burned tissue after major burns?

  1. Pure lymphatic obstruction blocking drainage from the tissues
  2. Excessive intravenous fluid infusion acting as the sole cause
  3. Increased permeability, low oncotic pressure, and altered Starling forces together
  4. Simple whole-body dehydration without any vascular changes
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Correct answer: Increased permeability, low oncotic pressure, and altered Starling forces together

Edema in burn injury results from increased capillary leakage, reduced oncotic pressure, altered Starling forces, and interstitial negative pressure, affecting both burned and non-burned tissues.

Difficulty: Medium Question 19 of 20

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