Nervous System Disorders · NCERT Biology

The use of L-Dopa (Levodopa) in Parkinson's therapy is based on the fact that:

  1. It inhibits acetylcholine
  2. It can cross the blood-brain barrier
  3. It directly stimulates muscle fibers
  4. It prevents amyloid plaque formation
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Correct answer: It can cross the blood-brain barrier

Dopamine itself cannot cross the blood-brain barrier to reach the brain. L-Dopa is a precursor that can cross the barrier and is then converted into dopamine by the enzyme DOPA decarboxylase.

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