Nervous System Disorders · NCERT Biology

Parkinson’s disease is primarily characterized by the progressive degeneration of neurons in which specific part of the brain?

  1. Hippocampus
  2. Cerebellum
  3. Substantia nigra
  4. Prefrontal cortex
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Correct answer: Substantia nigra

Parkinson's disease involves the progressive loss of dopaminergic neurons in the substantia nigra, a region within the basal ganglia. These neurons are essential for producing dopamine, which regulates smooth and coordinated voluntary muscle movements.

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