The accumulation of amyloid-beta plaques and neurofibrillary tangles is a pathological feature of:
Show answer and explanation
Correct answer: Alzheimer's disease
Alzheimer's is characterized by extracellular amyloid-beta plaques and intracellular tau protein neurofibrillary tangles. These protein aggregates disrupt cell signalling and eventually lead to widespread neuronal death and dementia.
Keep practicing
More Nervous System Disorders questions
- What is the primary early symptom observed in individuals suffering from Alzheimer’s disease?
- The 'shuffling gait' and 'mask-like face' are diagnostic physical signs associated with:
- Which protein is responsible for forming the 'neurofibrillary tangles' inside neurons in Alzheimer’s patients?
- Lewy bodies, which are abnormal aggregates of alpha-synuclein protein, are found in the neurons of patients with:
- Bradykinesia, a term used in the context of Parkinson's, refers to:
- Alzheimer’s disease leads to the atrophy of which specific brain region first?