Gastric Glands · Histology

Parietal cells secrete which substance essential for the absorption of Vitamin B12 in the ileum?

  1. Gastric lipase
  2. Intrinsic factor
  3. Somatostatin
  4. Bicarbonate ions
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Correct answer: Intrinsic factor

In addition to HCl, parietal cells produce intrinsic factor, a glycoprotein. Without intrinsic factor, Vitamin B12 cannot be absorbed by the distal small intestine, leading to pernicious anemia.

Difficulty: Medium Question 5 of 20

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