A 'venetian blind' appearance in a tissue section, characterized by parallel cracks or splits, is most frequently associated with:
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Correct answer: Tissue being too brittle or over-dehydrated
Over-processing, particularly excessive time in alcohols or heat, removes bound water and makes tissue brittle. This brittleness causes the tissue to crack or fracture during microtomy, resembling horizontal blinds.
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More Histological Artifacts questions
- Which of the following describes 'crush artifact' commonly seen in small biopsies?
- What is the likely cause of 'parched earth' or 'cracked' appearance in the tissue when viewed under the microscope?
- Which artifact is characterized by empty circular spaces within the cytoplasm of cells, often seen in frozen sections?
- The presence of a dark, opaque, granular precipitate throughout a section fixed in Zenker's or B-5 fixative is likely:
- If a tissue section appears 'cloudy' or 'milky' after clearing with xylene and before mounting, what is the most likely cause?
- What histological artifact is caused by the slow rate of fixative penetration, leading to enzymatic degradation of the tissue center?