Nucleus: Structure, Chromatin, Nucleolus · Zoology

The nucleolus is primarily involved in the synthesis of:

  1. Messenger RNA (mRNA) for protein-coding genes
  2. Transfer RNA (tRNA) for amino acid delivery
  3. Ribosomal RNA (rRNA) for ribosome biogenesis
  4. Deoxyribonucleic acid (DNA) for genome replication
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Correct answer: Ribosomal RNA (rRNA) for ribosome biogenesis

The nucleolus is the primary site of ribosomal RNA (rRNA) transcription by RNA polymerase I. Both large and small ribosomal subunits are partially assembled in the nucleolus before being exported to the cytoplasm, making the nucleolus central to ribosome biogenesis and thus to all cytoplasmic protein synthesis.

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