Cell Division: Mitosis and Meiosis · Zoology

Which checkpoint ensures all chromosomes are properly attached to spindle fibers before separation?

  1. G1 checkpoint, before DNA replication
  2. G2 checkpoint, before mitotic entry
  3. Spindle assembly checkpoint
  4. Restriction checkpoint in late G1
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Correct answer: Spindle assembly checkpoint

The spindle assembly checkpoint prevents anaphase onset until all chromosomes are correctly attached. This avoids chromosome missegregation.

Difficulty: Medium Question 10 of 20

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