Cell Division: Mitosis and Meiosis · Zoology

Which protein complex triggers the transition from metaphase to anaphase?

  1. Cohesin, holding sister chromatids together
  2. Separase, the cohesin-cleaving protease
  3. Anaphase-promoting complex
  4. Condensin, driving chromosome compaction
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Correct answer: Anaphase-promoting complex

The anaphase-promoting complex initiates degradation of securin. This allows separase to cleave cohesin and separate chromatids.

Difficulty: Medium Question 12 of 20

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