Cell Cycle: Phases and Checkpoints · Zoology

Which cyclin-CDK complex is most important for the transition from G1 to S phase?

  1. Cyclin A paired with CDK2
  2. Cyclin B paired with CDK1
  3. Cyclin D–CDK4/6
  4. Cyclin E paired with CDK1
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Correct answer: Cyclin D–CDK4/6

Cyclin D–CDK4/6 initiates progression through G1 and prepares the cell for S phase entry. It plays a critical role in responding to growth signals.

Difficulty: Medium Question 5 of 20

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